Water Mediated Proton Hopping Empowers Proteins

Abstract

Quantum dynamics simulations are used to test and validate the hypothesis that enhanced electronic activity and energetic efficiency in hydrated proteins are due to water-mediated proton hopping between peptide and peptenol states. Water is thereby an integral part of the electronic structure of a ‘live’ protein prior to denaturation.

Authors
David Porter and Fritz Vollrath

Journal

Soft Matter, 2013,9, 643-646
DOI: 10.1039/C2SM27155A

Link

http://pubs.rsc.org/en/content/articlelanding/2013/sm/c2sm27155a#!divAbstract